Normal soaking extraction (NSE) method was carried out for 14 hours using seven different types of solvent systems of (1) acetone (2) methanol (3) acetonitrile (4) DES (5) DES + methanol (6) DES + acetonitrile and (7) OTf + acetone. Finally, a summary of applications of DESs in various extraction processes (phenolics, fuels, metals, proteins, carbohydrates), solid-phase extraction, solid-phase microextraction, as well as capillary electrochromatography is = C-NMR. ![]() Since polarity is an important aspect in their use in separations, the classification of DESs based on the betaine dye and nile red scales as well as Kamlet-Taft parameters is also discussed. This work discusses all methods of DES preparation and details their advantages and disadvantages. However, due to the diverse range of hydrogen bond acceptors and donors that comprise DESs, choosing the appropriate solvent for separations can be challenging. ![]() Their tunable and designer physio-chemical properties, low cost, and ease of preparation make them attractive solvent systems for use in extractions and additives to chromatographic separations. Deep eutectic solvents (DESs) have emerged as alternatives to conventional organic solvents and ionic liquids (ILs).
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